Given that EGFR and integrin αvβ3 are often concurrently overexpressed in various malignant tumors [68,69], Chen et al. enhanced tumor imaging specificity and sensitivity by conjugating Pep4 with the integrin-targeting peptide RGD and labeling it with 68Ga to create the dual-receptor PET probe 68Ga-NOTA-RGD-Pep4 [70]. Here, EGFR is linked to neoplasm.