Furthermore, the survival analysis of the cancer cells hub-genes indicated that GAPDH, AKT1, CS, RHOA, TPI1, SDHA, FASN, HIF1A, FN1, COL1A1, COL1A2, COL3A1, COL5A2, COL5A1, BGN, COL6A2, FBN1, USP7, CDK9, H2BC9, and NOP2 exhibited insignificant p-values. The gene discussed is COL1A1; the disease is cancer.