The protein network of unique cancer cell genes in the “cancer-PDAC_vs_all-normal” group showed top 10 hub genes, including FN1, COL1A1, COL1A2, COL3A1, COL5A2, COL6A1, COL5A1, BGN, COL6A2, and FBN1, showing 62, 59, 56, 55, 51, 50, 50, 48, 46, and 45 interactions within the protein network, respectively. The gene discussed is COL6A1; the disease is cancer.