Lastly, the markers unique to the “cancer-PDAC_vs_all-normal” group included Extracellular matrix organization, Collagen formation, Assembly of collagen fibrils and other multimeric structures, Collagen degradation, Collagen biosynthesis and modifying enzymes, Degradation of the extracellular matrix, ECM proteoglycans, Collagen chain trimerization, MET activates PTK2 signaling, and Integrin cell surface interactions as the top 10 enriched pathways. Here, PTK2 is linked to cancer.