The protein network of common cancer cell genes showed the top 10 hub genes, including GAPDH, AKT1, EGFR, CS, RHOA, TPI1, SDHA, TFRC, FASN, and HIF1A; the network showed 364, 284, 242, 212, 207, 200, 189, 189, 186, and 179 interactions, respectively. The gene discussed is HIF1A; the disease is cancer.