While the markers unique to the “cancer cells_vs_all-PDAC” group included Gene expression (Transcription), Generic Transcription Pathway, RNA Polymerase II Transcription, Metabolism of RNA, DNA Repair, Antiviral mechanism by IFN-stimulated genes, SMAC (DIABLO) binds to IAPs, SMAC (DIABLO)-mediated dissociation of IAP complexes, Abasic sugar-phosphate removal via the single-nucleotide replacement pathway, and SMAC, XIAP-regulated apoptotic response as the top 10 enriched pathways. The gene discussed is DIABLO; the disease is cancer.