The protein network of unique cancer cell genes in the “cancer cells_vs_all-PDAC” group exhibited top 10 hub genes, including H4C6 (HIST1H4A or HIST1H4C), MYC, H3C12 (HIST1H3A or HIST1H3D), DDX21, USP7, RFC4, APEX1, CDK9, H2BC9 (HIST1H2BH), and NOP2. The gene discussed is USP7; the disease is cancer.