HASPIN and colorectal cancer: In our previous work, we demonstrated that the intraperitoneal administration of CHR-6494, an inhibitor of the serine–threonine kinase HASPIN, in ApcMin/+ mice—a model of familial colorectal cancer—inhibited both the development of colorectal cancer and testicular atrophy due to impaired spermatogenesis, while restoring blood testosterone levels [3].