To evaluate the effects of intraperitoneal injection of 9‐ING‐41 on cognitive function and the molecular mechanisms in ApoE4‐T2DM mice, we observed that 9‐ING‐41 significantly increased Syn‐1 level without affecting GluR2 and synaptophysin (SYP) levels in the hippocampus of E4‐T2 mice (Figure 8a,b). Here, GRIA2 is linked to type 2 diabetes mellitus.