Based on the calculations and statistical analysis across the two strains of rats (WKY and SHR), three age stages (3-week-old, 12-week-old and 44-week-old), two aortic segments (AA and TA), two surfaces of the aortic wall (internal and external) and two types of fibres (collagen and elastin), features that hold considerable promise for revealing and quantifying hypertension-induced aortic fibre remodelling were identified. The gene discussed is ELN; the disease is hypertensive disorder.