ACTH: adrenocorticotropic hormone; AD: autosomal dominant; AR: autosomal recessive; CAH: congenital adrenal hyperplasia; CAKUT: congenital anomalies of kidney and urinary tract; PHA: pseudohypoaldosteronism; UTI: urinary tract infection. The gene discussed is POMC; the disease is congenital adrenal hyperplasia.