There are several differential diagnoses for patients with DM, hepatomegaly, and elevated transaminase levels, which include: GH, which is most likely in patients with T1DM, NAFLD, mainly in T2DM patients, celiac disease, autoimmune hepatitis, viral hepatitis, hemochromatosis, and Wilson's disease [7, 26]. The gene discussed is GH1; the disease is diabetes mellitus.