FOXO1 and Disorder of lipid metabolism: Suzuki et al. (40) reported that a highly absorbable catechin extract prevented diet-induced lipid-metabolism disorder in mice through marked inhibition of hepatic Srebp-1c expression, while Kim et al. (41) showed that (−)-epigallocatechin gallate blocked 3 T3-L1 adipocyte differentiation via the FoxO1/Srebp-1c axis.