Although research on LSD1 in PM is limited, in other solid tumors, LSD1 inhibition has been found to enhance tumor immunogenicity and T‐cell infiltration in immunogenically “cold” tumors, transforming them into “hot” tumors with active immune responses and significantly improving the efficacy of PD‐1/PD‐L1 ICIs [157]. This evidence concerns the gene PDCD1 and neoplasm.