MPZ and Charcot-Marie-Tooth disease: Over 100 genetic mutations cause CMT, which can be inherited in different ways, including autosomal dominant, such as mutation in peripheral myelin protein 22 (PMP22) and myelin protein zero (MPZ), autosomal recessive mitofusin 2 (MFN2), gang-lioside-induced differentiation-associated protein 1 (GDAP1), SH3 domain and tetratricopeptide repeats 2 (SH3TC2), and X-linked inheritance patterns, including gap junction beta 1 (GJB1) [50].