In comparison with vehicle controls, tumor-bearing mice fed with SX-682 chow showed an increase in the TME of CD45+ total tumor-infiltrated leukocytes (Figure 3C), including CD3+CD45+ T cells (Figure 3D) in the TME, an increase in CD8+ T cells (Figure 3E), an increase in CD69+ activated CD8+ T cells (Figure 3F), and an increase in the percentage of CD4+CD44+ T cells (Figure 3I). The gene discussed is CD44; the disease is neoplasm.