ARPC1B and neoplasm: Subsequently, three approaches (pseudobulk, singlecell DE, and hdWGCNA) were integrated (hub genes are summarised in Table S2) and identified ARPC1B as an overlapping hub gene (Figure 1L), showing significant upregulation in gemcitabine‐resistant CSCs compared to non‐resistant CSCs and in tumour samples versus normal tissues (Figure 1M,N).