Previous studies in ccRCC suggested a prognostic relevance of selected lipid metabolic genes such as fatty acid synthase [9,10], enoyl-CoA hydratase short-chain 1 (ECHS1) [11], HDL-Receptor SR-BI [12], the lipid transporter CD36 [13], FA catabolic enzymes CPT1A, HADHA, HADHB and ACAT1 [10,14] or the fatty acid transport protein 4 [15]. Here, FASN is linked to nonpapillary renal cell carcinoma.