In our bulk RNASeq data, we observed an upregulation of two caspase antagonists (BIRC2, BIRC3) as well as downregulation of two pro-apoptotic proteins (BIK, BAX) in cells that had survived infection with a Vpr-expressing virus for two weeks, while a different apoptosis gene (BCL2L11), a pro-necroptosis pathway gene (ZBP1), and a pro-pyroptosis gene (GSDME) were upregulated (Table 1). This evidence concerns the gene GSDME and infection.