TTN and hydrops fetalis: Several HF-associated genes have been identified, including FHOD3, a gene linked to cardiomyopathy and HF [11]; Titin (TTN) and MYH7, which are associated with cardiomyopathy progression [12,13]; NPPA, which encodes atrial natriuretic peptide regulating fluid balance [13]; and BMP4, involved in cardiac development and signaling pathways [14].