PRNP and Creutzfeldt Jacob disease: Of the definite CJD positive controls utilized for our assay development, only 1 has undergone molecular subtyping (CJD3 is a T2MM, as per the “London/Collinge nomenclature”15) Nevertheless, CJD2 and CJD4 were both known to be PRNP polymorphic codon 129 (c129) valine homozygotes.