TF and migraine disorder: However, the Tf/E2 ratio was significantly higher in the migraine group (2.6, IQR 1.4) than in the control group (1.9, IQR 1.1; p = 0.01), whereas the total T/E2 ratio and the Tc/E2 ratio showed no significant differences (T/E2: 154.4, IQR 111.4 vs. 117.8, IQR 85.2; p = 0.27 and Tc/E2: 168.0, IQR 113.0 vs. 122.9, IQR 85.5; p = 0.19).