Further PPI analysis of these targets revealed that 6052 edges were presented, of which TNF (degree = 218), IL6 (degree = 202), IL1β (degree = 194), PTGS2 (degree = 188), INFG (degree = 168), NFKBIA (degree = 140), ICAM1 (degree = 140), VCAM1 (degree = 132), RELA (degree = 128), and NOS2 (degree = 96) inflammatory targets had higher degree values (Figure 5B), suggesting that these targets were co‐involved in the onset and progression of ALI. This evidence concerns the gene IL6 and acute respiratory distress syndrome.