Further PPI analysis of these targets revealed that 6052 edges were presented, of which TNF (degree = 218), IL6 (degree = 202), IL1β (degree = 194), PTGS2 (degree = 188), INFG (degree = 168), NFKBIA (degree = 140), ICAM1 (degree = 140), VCAM1 (degree = 132), RELA (degree = 128), and NOS2 (degree = 96) inflammatory targets had higher degree values (Figure 5B), suggesting that these targets were co‐involved in the onset and progression of ALI. The gene discussed is NOS2; the disease is acute respiratory distress syndrome.