Furthermore, considering that PSMA1 is a biomarker of NETs, we found that when PSMA1 expression was reduced, the expression of NET markers (Cith3 and MPO) was also decreased (Figure 7G); furthermore, immunofluorescence demonstrated that the rate of colocalization between NET markers (Cith3 and MPO) and neutrophils in PCa tissues was greater than that in normal prostate tissue (Figures 7H, I), suggesting that PSMA1 can effectively promote the synthesis and release of NETs. This evidence concerns the gene PSMA1 and posterior cortical atrophy.