Two further hypoxia-regulated genes were induced, namely HIF2 and VEGFA. In summary the most important information we concluded from this part of the study is: In SHR/NCrl rats the expression of atypical but brain-specific UCP isoforms is altered in comparison to both normotensive rats and SHR strains without ADHD phenotype. This evidence concerns the gene UCP1 and attention deficit-hyperactivity disorder.