Variables with P < 0.05 in the univariate Cox regression analysis (HE4, NYHA-FC, eGFR) and variables that are clinically associated with the prognosis of patients with HFpEF (e.g., age, diabetes, E/e′, and NT-proBNP) were included in the multivariate Cox regression analysis. Here, NPPB is linked to diabetes mellitus.