Another meta-analysis, including a total of 1,101 adult participants with type 2 diabetes or prediabetes, demonstrated that intermittent fasting (IF) led to significant reductions in body weight (−4.56 kg), body mass index (−1.99 kg/m2), HbA1c (−0.81%), fasting glucose (−0.36 mmol/L), total cholesterol (−0.31 mmol/L), and triglycerides (−0.14 mmol/L), without exerting a significant impact on fat mass, insulin levels, LDL, HDL, or blood pressure compared to control groups (133). The gene discussed is INS; the disease is type 2 diabetes mellitus.