The input variables comprised independent attributes such as procedure side, histopathology, preoperative FSH, preoperative testosterone, testicular volume, Klinefelter’s syndrome, cryptorchidism, cancer history, varicocele, idiopathic Non Obstructive Azoospermia (NOA), age, FSH classification, testosterone classification, and interval. The gene discussed is BRD2; the disease is Klinefelter syndrome.