AFP and hepatocellular carcinoma: Additionally, the serum level of AFP was significantly positively associated with HCCEvoSig risk scores in both training and validation datasets across RNA-seq-based and microarray-based platforms (Figures 5N,O and Supplementary Figure S6N-O; p < 0.01 for TCGA-LIHC, CHCC-HBV, Mongolian-HCC, and FULCI-HCC cohorts).