GA can sensitize TNF-related apoptosis-inducing ligand (TRAIL)-mediated renal carcinoma Caki cell apoptosis via downregulating cFLIPL (Jang et al., 2016), and it also sensitizes TRAIL-resistant breast cancer cells to TRAIL-induced apoptosis (Wang S. et al., 2018). The gene discussed is CFLAR; the disease is renal carcinoma.