Univariate analysis showed that age, tumor size, pathological type, surgical method, T stage, N stage, TNM stage, neural invasion, lymphatic vascular invasion, LNH, TP, HB, ALB, CEA, CA19-9, CA125, AFP levels, monocyte, lymphocyte, RBC and platelet counts were risk factors for MLM in gastric cancer. This evidence concerns the gene AFP and gastric cancer.