MLANA and melanoma: Pathology (right breast 9C, left breast 11C) indicated malignant melanoma based on immunohistochemistry: tumor cells were P63 (-), P40 (-), Vimentin (+), CK5/6 (-), CK (-), EMA (-), SMA (-), Syn (-), CgA (-), CD56 (+), Calponin (-), PR (-), ER (-), P120 (membrane +), E-Cadherin (+), CerbB-2 (0), CD10 (focal +), S-100 (+), Melan-A (+), HMB45 (+), and Ki-67 (+, approximately 70%) (Figures 3A–H).