Of note, in DF-1 cells, the virus expressing NS100 stimulated a higher level of TNF-α RNA than WT NS1 at 24 hpi, although IFN-β and Mx levels remained lower levels under NS100 virus than RG-AIV-WT virus infection at 12 hpi (Figure 3(C)). The gene discussed is IFNB1; the disease is viral infectious disease.