IL17A and hypertensive disorder: Dendritic cells play a crucial role in immune-dependent blood pressure elevation by interacting with T cells to generate memory effector T cells to promote HTN.97 T helper 17 cells are also associated with HTN development in animal models through the production of interleukin-17 (IL-17).98,99 Furthermore, IL-17 knockout mice and IL-17 receptor blockade displayed the reduction of blood pressure, implicating an important role of IL-17 in regulating blood pressure.100