Additionally, integrin αvβ6 activates MMPs activity and increases extracellular matrix degradation to promote EMT and the migration of post‐EMT cells on fibronectin in cancers.[43, 44] Integrin αvβ6 promotes lung cancer cell proliferation, migration, and invasion by impairing the expression of MMP2 and MMP9 and induces tumor growth by inhibiting cancer cell apoptosis. Here, FN1 is linked to cancer.