MMP2 and neoplasm: Additionally, integrin αvβ6 activates MMPs activity and increases extracellular matrix degradation to promote EMT and the migration of post‐EMT cells on fibronectin in cancers.[43, 44] Integrin αvβ6 promotes lung cancer cell proliferation, migration, and invasion by impairing the expression of MMP2 and MMP9 and induces tumor growth by inhibiting cancer cell apoptosis.