CD19 and leukemia: Similarly, in a KMT2A::AFF1 patient-derived xenograft model in which leukemia cells express lower levels of CD19 and CD133 than SEM cells (Figure 3E), 5 × 106 bispecific CAR-iNKT cells at day 15 eradicated leukemia in vivo in patient-derived xenograft–engrafted animals (Figure 3F-H).