Upregulated genes were enriched in extracellular matrix and structure organization, indicating their involvement in cancer microenvironment reconditioning.[32] Additionally, they were associated with essential CCs and pathways like focal adhesion, suggesting their roles in cancer cell proliferation, viability, adherence, movement, infiltration, and metastasis.[33] The PI3K/AKT pathway is commonly overstimulated in various human cancers. The gene discussed is AKT1; the disease is cancer.