To investigate whether STAT3 binds to the promoter region of ERCC4 and how CXCL14 enhances its expression in bladder cancer cells, we overexpressed STAT3 in 293 T cells (Fig. S4B) as an external validation and modulated STAT3 phosphorylation in T24 cells with rhCXCL14 or rhCXCL14 combined with STAT3i (Fig. S4C). Here, ERCC4 is linked to urinary bladder cancer.