We then treated bladder cancer cells with CM from different groups, and immunofluorescence staining of γH2AX revealed decreased DNA damage in T24 and UM-UC-3 cells incubated with CAFs/CM, which lost their protective role after CXCL14 expression was modulated (Fig. 3H, K). Here, CXCL14 is linked to urinary bladder carcinoma.