In this regard, we verified that TS1, a lipid-soluble phenanthraquinone extracted from the root of TCM Salvia miltiorrhiza and displaying favorable activities in antioxidant, anti-inflammatory, anti-cancer as well as plays a role in the regulation of cell autophagy or apoptosis [33], can synergize with Ara-C to induce apoptosis in ALL cells by reducing STAT6 expression. This evidence concerns the gene STAT6 and acute lymphoblastic leukemia.