Functionally, MyBP-C contributes to contractile function by stimulating cardiac actomyosin ATPase or influencing myofibril tension generation and contractile velocity.45 A DCM mouse model was engineered encoding a truncated form of MyBP-C which altered the MHC-binding and titin-binding domains45. The gene discussed is TTN; the disease is familial dilated cardiomyopathy.