[140] further expanded the application of all-dielectric metasurfaces in the field of biomedical detection and proposed a THz metasurface biosensor based on silicon pillar arrays for ultrasensitive detection of tumor markers CA125 and HER2, as shown in Fig. 9C. Unlike existing studies, in this work, specific detection of tumor markers was achieved by antigen–antibody specific modification on the surface of the silicon pillar array. The gene discussed is ERBB2; the disease is neoplasm.