Histopathologically, schwannomas classically display Antoni A and/or Antoni B patterns, with nuclear palisades that form Verocay bodies. Immunohistochemistry of the tumor cells typically demonstrates diffuse and strong S100 antigen positivity, with variable CD34, calretinin, TLE1, podoplanin, and SOX2 expression [17]. The gene discussed is TLE1; the disease is neoplasm.