Vitamin D receptors are present in vascular smooth muscle, endothelium, and cardiomyocytes, suggesting that its deficiency may adversely affect cardiovascular function through mechanisms such as endothelial dysfunction, inflammation, and increased arterial stiffness [3]. Vitamin D regulates nitric oxide (NO) synthesis in endothelial cells, playing a protective role against endothelial dysfunction (ED), a precursor to atherosclerosis. This evidence concerns the gene VDR and endothelial dysfunction.