TNF and autoimmune disease: IL-17A is an important proinflammatory cytokine produced by Th17 cells, attracting neutrophils and monocytes, activating inflammation, and inducing the secretion of some important inflammatory factors such as IL-6, TNFα, etc. Abnormal IL-17 levels were supposed to play an important role in autoimmune diseases through different processes such as adhesion, recruitment, cell proliferation, and inflammation.