Decreased mRNA levels of IL-6 by FH whilst its elevation in FP or TSR4 + 5 treated cells appear to suggest that FH might prevent the transition of SARS-CoV-2 infection to the severe form of the disease through limiting dysregulation of IL-6 levels, whereas FP may contribute to promoting IL-6 abnormality. This evidence concerns the gene IL6 and familial hyperaldosteronism.