Furthermore, the presence of FH led to a decrease in the expression levels of proinflammatory cytokines and chemokines, including IL-1β, IL-8, IL-6, TNF-α, IFN-α, NF-κB, and RANTES whereas these pro-inflammatory mediators were increased in the case of FP. The gene discussed is CXCL8; the disease is familial hyperaldosteronism.