GPT and Pallister-Hall syndrome: We first evaluated the potential toxic effects of PHS by assessing liver, kidney, and cardiac function markers, finding no significant differences in alanine aminotransferase (ALT), aspartate aminotransferase (AST), urea nitrogen (BUN), creatinine (CR), lactate dehydrogenase (LDH), and creatine kinase (CK) among the groups.