MAPT and Alzheimer disease: Molecular dynamics (MD) simulations using platforms like GROMACS or AMBER can elucidate the stability and interaction dynamics of polyphenol candidates (curcumin, EGCG, resveratrol) with AD‐related targets such as amyloid‐β, tau protein, and acetylcholinesterase, leveraging crystallographic data from PDB entries (Gheidari et al. 2024).