MAPT and Alzheimer disease: The pathogenesis of AD is multifactorial, involving the accumulation of amyloid‐beta (Aβ) plaques, neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau protein, oxidative stress, and chronic neuroinflammation (García‐Morales et al. 2021; Simunkova et al. 2019).