Similarly, (Wu et al. 2021) synthesized novel naringenin carbamate derivatives, with compound 5 g exhibiting potent acetylcholinesterase (AChE) inhibition (IC50 = 0.42 μM), antioxidant activity, and metal chelating properties, leading to the mitigation of the adverse effects of AD pathology. Here, ACHE is linked to Alzheimer disease.