Since the expression of LPC (20:4) showed a downward trend in both AMI groups (P < 0.05, FC < 0.67, VIP>1) and LPC (20:4) is positively correlated with left ventricular ejection fraction and APOA, we considered LPC (20:4) to be an important biomarker in the pathophysiology of myocardial infarction. Here, VIP is linked to myocardial infarction.