IFNA1 and viral infectious disease: We then assessed the IFN response to a viral infection by inoculated COs from HC1 and CAN1 iPSC lines with one of two orthobunyaviruses, La Crosse virus (LACV) or Inkoo virus (INKV), which are known to infect neurons and induce IFN responses(Winkler et al., 2019).