A second example of a cluster of epilepsy disease genes is shown in Figures 6d–6e, where four members of the gamma-aminobutyric acid type A receptor gene family (GABR family, n = 4) reside adjacent to a VERT region; notably, GABRA1 displays AEI (Fig. 6e, and Supplementary Table 2), and mutations in GABRA1, GABRB2, and GABRG2 cause autosomal dominant developmental and epileptic encephalopathies 29,53,54. The gene discussed is GABRG2; the disease is epilepsy.