Additionally, an examination of immune cell markers has shown that MDSCs and the M2 subtype of TAMs can notably enhance the expression of SNHG25. It is widely recognized that various immune cell types, including T cells, neutrophils, macrophages, NK cells, dendritic cells, and B cells, exist in the TME and play a pivotal role in cancer biology [32, 33]. Here, SNHG25 is linked to cancer.