Gene set enrichment analysis (GSEA) of all DEGs demonstrated marked functional disparities between AS and control samples, particularly in targets of RUNX1 RUNX1T1 fusion erythrocyte, melanoma, β-IFN–treated bronchial epithelial cells, Class A1 rhodopsin-like receptors, and tumor rejection (Figure 2I). Here, RUNX1T1 is linked to melanoma.