Lower Aβ42 was associated with older age (β=−0.17, 95%CI=−0.24 – −0.09, p<0.001), APOE ε4 carriers (β=−0.18, 95%CI=−0.33 – −0.03, p=0.020), higher BMI (β=−0.18, 95%CI=−0.26 – −0.10, p<0.001), and higher eGFR (β=−0.53, 95%CI=−0.63 – −0.42, p<0.001); no other factors were significant (ALT β=−0.07, 95%CI=−0.14 – 0.00, p=0.065; diabetes β=0.14, 95%CI=−0.02 – 0.30, p=0.092; all other p≥0.11). This evidence concerns the gene APOE and diabetes mellitus.