UMOD-positive/PROM-1 negative cast subtypes (UMOD-positive/PROM1-negative/IGFBP7-positive casts and UMOD-positive/PROM1-negative/IGFBP7-negative casts) were associated with higher odds of AKI rather than CKD (Figure 2D). Here, IGFBP7 is linked to acute kidney injury.