Time-stratified analyses for non-germinal center-derived B-cell lymphoma revealed 4 proteins (FCMR, FCRL3, SEMA4A and SLAMF6) associated with non-germinal center-derived B-cell lymphoma from early development (> 10 years before diagnosis) until less than 5 years before diagnosis (Supplementary Fig. 10FGHJ). Here, FCRL3 is linked to B-cell non-Hodgkin lymphoma.